Pyrilutamide KX-826 0.5% topical solution bottle — Folliva Labs
Folliva labs.

Pyrilutamide 0.5%

4.616 reviews
  • Every batch tested by an independent lab before it ships
  • A newer antiandrogen for people who react to RU-58841
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Batch and date on every bottle
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Formulated & tested in the EU
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How it differs from RU-58841

Same job, different design. Pyrilutamide is a newer molecule intended to act at the scalp and then break down rather than build up. Some men tolerate one better than the other. Run one receptor blocker or the other — not both at once.

What to expect, honestly

The human evidence for pyrilutamide is real but limited, and the full picture is not settled — so treat your own six-month photographs as the verdict that matters. Some early shedding as follicles reset is common. Judge it at six months, on pictures.

Suitability & safety

For research use only. Not a medicine, and the safety data is thinner than for approved options. Patch-test first, use one blocker at a time, and speak to a professional if you are unsure.

Batch & storage

Every bottle is stamped with its batch number, blend date and expiry. Store it cool, dry and out of direct light — it degrades with heat and daylight.

HOW IT WORKS

Same target as RU-58841. A different key.

Pattern hair loss comes down to one hormone delivering the same instruction to your follicles, cycle after cycle. Pyrilutamide blocks that instruction at the receptor — the newer of two ways Folliva does the same job.

  1. 01

    DHT reaches the follicle

    Testosterone converts into DHT. In a susceptible scalp it binds androgen receptors inside the follicle and tells it to shrink. The receptor is the lock; DHT is the key.

  2. 02

    The follicle miniaturises

    Each cycle that signal lands, the growth phase shortens and hair returns finer and weaker. This runs quietly for years before a mirror admits it.

  3. 03

    Pyrilutamide occupies the receptor

    It is a nonsteroidal androgen-receptor antagonist. It sits in the receptor so DHT cannot deliver its instruction — on the scalp, where the damage happens.

  4. 04

    Designed to stay local, then clear

    It is built to act at the scalp and break down rather than accumulate in the body — an antiandrogen you apply, not one you swallow.

Why you’d choose it over RU-58841

Same target, different molecule. The main reason to run pyrilutamide is tolerance: some men find it sits better on their scalp than RU. It is not stronger — it is an alternative route to the same receptor.

One blocker at a time

RU-58841 and pyrilutamide do the same job. Running both does not double the effect; it just doubles what can irritate your scalp. Pick one, give it six months, judge it on photographs.

What the evidence actually is

Pyrilutamide has human trial data — which puts it ahead of many topicals — but that data is still limited and the picture is not settled. It is a research compound, not an approved medicine. What we can be held to is the bottle: blended at 0.5% by us in the EU, lab-tested every batch, dated so you know how old yours is.

THE ROUTINE

It takes sixty seconds a day.

It comes as a spray pump. One application a day, onto a dry scalp.

  1. 01

    Count the pumps

    Six to seven pumps of the spray is roughly 1 ml — the daily dose. It is a spray pump, so you count it. More is not better: a receptor can only be occupied once.

  2. 02

    Apply to a dry scalp

    Part the hair and spray onto the skin over the thinning area, not the hair. The scalp is where the receptors are.

  3. 03

    Let it dry

    Spread it gently and let it dry fully. Nothing to wash out.

  4. 04

    Same time, every day

    Consistency beats quantity. Photograph the same spot monthly in the same light.

Research use only. Batch number, blend date and expiry are printed on the bottle.

WHAT TO EXPECT

Nothing happens for a while. That’s normal.

A receptor blocker holds the line before it grows anything back. The early months are quiet by design.

  1. WEEKS 0–4

    Baseline, maybe a shed

    Take your first photographs. Some shedding as follicles reset is common and reads like failure. It usually isn’t.

  2. MONTHS 1–2

    Shedding settles

    Loss slows before anything grows. This is where most people quit too early.

  3. MONTHS 3–4

    First new growth

    Fine, pale hairs at the hairline and temples — easy to miss without your baseline photo.

  4. MONTHS 6+

    An honest verdict

    Six months is the earliest fair judgement, and with pyrilutamide’s limited evidence your own photographs matter more than anyone’s claims.

REVIEWS

What people actually report.

Unedited accounts from people using this. Individual results and timelines vary.

4.6
Excellent16 reviews
  • el_greco27 June 2026, 8:08 pm

    early days but easy to use and no sides

    Verified buyer

  • Nikolas G.29 March 2026, 11:22 pm

    did my reading on this one, cautiously optimistic

    Verified buyer

  • Hugo19 March 2026, 12:46 pm

    shed settled around week 8

    Verified buyer

  • marek19 March 2026, 11:57 am

    a bit skeptical since its newer but so far good

    Verified buyer

  • Verified buyer25 January 2026, 7:25 am

    came over from oral, no complaints yet

  • J.L.9 January 2026, 3:33 am

    fast shipping, sealed and dated

    Verified buyer

  • Rafal10 December 2025, 11:43 am

    too early to judge but the application is clean and painless

    Verified buyer

  • Karim L.29 November 2025, 7:50 am

    glad someone in the EU actually stocks this properly

    Verified buyer

  • dan_9229 August 2025, 8:51 am

    plain packaging, quick delivery, straight answers by email

  • Lucas J.7 August 2025, 1:15 pm

    just started but ordering was smooth and quick

    Verified buyer

  • Julius Laan9 June 2025, 5:49 am

    using it with my routine, scalp handles it fine

    Verified buyer

  • Jonas7 June 2025, 4:57 am

    wanted something topical not a pill, this fits

    Verified buyer

  • Julius M.7 April 2025, 2:01 pm

    dries fast, no itch on my scalp

  • N3 April 2025, 1:50 am

    2 months in, hairline seems to be holding

    Verified buyer

  • Marek Berg1 April 2025, 11:13 pm

    less shedding after the first month or so

    Verified buyer

  • milan_18 March 2025, 10:47 am

    switched from RU to try this, no irritation so far

    Verified buyer

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FAQ

Questions, answered.

How is it different from RU-58841?

Same job, different design. Pyrilutamide is newer and built to act at the scalp then break down rather than accumulate. The usual reason to choose it is tolerance — some men find it sits better on their skin than RU. Run one blocker or the other, never both.

How do I use it?

Six to seven pumps of the spray is about 1 ml — the daily dose. Apply to a dry scalp once a day and let it dry. It is a spray pump, so you count it; there is nothing to measure.

How strong is the evidence?

Pyrilutamide has human trial data, which puts it ahead of most topicals. But that data is still limited and the picture is not fully settled. It is a research compound, not an approved medicine, and we won’t pretend the case is closed.

Are there side effects?

Being topical, it is designed to avoid the systemic effects of oral blockers, but the safety data is thinner than for approved options. Patch-test first and stop if you react.

How do I know it is genuine?

We blend it at 0.5% in the EU and an independent laboratory tests every batch before it ships. Every bottle carries its batch number, blend date and expiry.

Shipping and returns?

Shipped from the EU, usually 2–5 working days, in plain unbranded packaging. Unopened bottles can be returned within 14 days.