RU58841 5% topical solution by Folliva Labs — 50 ml amber-black glass bottle with spray pump, blended in the EU
RU58841 topical solution bottle, Folliva Labs label showing concentration and volume
Folliva Labs topical DHT blocker, 50 ml black glass bottle with gold spray pump, RU58841 5% on the label
Man holding the Folliva Labs DHT blocker spray bottle in a bathroom, once-a-day scalp application
Close-up of the fine-mist pump spraying, showing the droplet pattern used to apply the solution to the scalp
Folliva Labs bottle beside a lab vial, pipette and a printed certificate of analysis on a slate bench
Folliva Labs

#1 Strongest Hair Loss Solution - Maximum Strength Topical DHT Blocker

4.988 reviews
Concentration
Volume
Purchase options
UNIT PRICE €71,99
QUANTITY
Blocks DHT at follicle receptors
Janoshik, COA Tested
>99% purity verified
No prescription
Fast EU delivery — order today
What is RU?

RU is a nonsteroidal androgen receptor antagonist, first developed in the 1990s and never taken to market. It is a research compound. It is not an approved medicine, and no regulator has assessed it for hair loss. We are not going to dress that up.

How it works

Pattern hair loss is a signalling problem. DHT binds androgen receptors inside the follicle and instructs it to shrink; every cycle it lands, the hair comes back finer, until one cycle it doesn't come back at all.

RU occupies that receptor. With the receptor taken, DHT has nowhere to deliver the instruction. It is designed to do this in the skin you put it on rather than by lowering DHT throughout your body the way an oral blocker does — which is the reason most people who find their way to it are coming off finasteride rather than starting it.

What it does not do: push growth. It removes the thing causing the loss. If you want an accelerator as well, that is what minoxidil is for.

How to use it

Six to seven pumps is roughly 1 ml -1,5 ml — that is the daily dose. Part the hair and put it on the scalp, not the hair; the receptors are in the skin. Let it dry fully. Nothing to rinse.

Once a day, same time, ideally at night. More is not better — a receptor can only be occupied once, and the surplus buys you irritation, not hair. Photograph the same spot, same light, once a month.

What to expect, honestly

Weeks 0–4: nothing visible, and possibly more shedding than usual as follicles reset their cycle. It reads like failure. It usually isn't.

Months 1–2: the shedding settles. Loss slows before anything grows. This is where most people quit.

Months 3–4: fine, pale hairs at the temples and hairline — easy to miss without the baseline photo you took in week one.

Month 6+: the earliest point a fair verdict is possible. Compare photographs, not memories. Some people hold the line and never regrow much; holding the line is itself the result.

Suitability and safety

There are no completed clinical trials in humans, so there is no safety profile in the sense a medicine has one. What exists is preclinical work and two decades of self-reported use.

Patch-test on a small area first. Stop if the skin reacts. Do not use it if you are pregnant, breastfeeding or trying to conceive. If you are on any prescribed treatment, or you have a scalp condition, speak to a doctor before you start — and if you would rather have an approved medicine with trial data behind it, finasteride and minoxidil are exactly that, and we will tell you so.

Batch, freshness and storage

Every bottle have lot number, blend date and expiry. That matters more here than it does for most things: RU58841 degrades over time, so a bottle's age is part of what you are buying. We blend in small runs for that reason rather than filling a warehouse.

Store it cool, dry and out of direct sunlight. The certificate of analysis for your lot is available on request.

Read this before you buy

" RU is a research compound. It is not an approved medicine in the EU, no regulator has assessed it for hair loss, and nobody can promise you an outcome — us least of all. What we can do is tell you exactly what is in the bottle, how old it is, and who tested it. If that isn't enough for you, don't order; write to us instead. "

REVIEWS

What people actually report.

Unedited, good and bad, including the ones about slow parcels. Individual results and timelines vary, and some people get nothing.

  • jakub9 July 2026, 6:40 pm

    Great service, package here in 3 days

    Verified buyer

    Folliva Labs replied

    Cheers, glad it turned up quick.

  • Sven9 July 2026, 1:05 am

    tried loads of stuff over the years and this is the first that actually held the line

    Verified buyer

    Folliva Labs replied

    Glad it stuck for you where the others didnt. Cheers.

  • Youssef K.8 February 2026, 12:34 pm

    Took about two weeks to turn up and the tracking sat frozen for days, was getting annoyed ngl. product itself is good but the wait sucked

    Verified buyer

    Folliva Labs replied

    Really sorry about that one. It got stuck at customs and sat far too long. We sent you a second bottle free straight away. Anytime a tracking number stops moving for a few days just email us and we sort it.

  • Emre J.7 July 2026, 11:31 pm

    package took a bit longer but got here fine

    Verified buyer

  • Finn G.3 July 2026, 5:56 pm

    stopped my recession dead. wish i found this years ago

    Verified buyer

  • Henrik D.26 May 2026, 7:43 pm

    legit seller, fast delivery

    Verified buyer

  • sander8812 May 2026, 11:32 pm

    my barber noticed the temples filling in before i did lol

    Verified buyer

  • Julius Kaiser3 May 2026, 1:29 pm

    quick delivery cheers

    Verified buyer

  • Karim2 May 2026, 3:45 am

    quik and easy, will order again

    Verified buyer

  • Rasmus Z.28 April 2026, 8:59 am

    came off fin because of the sides, no sides with this and my hairline is holding. relieved honestly

    Verified buyer

  • finn24 April 2026, 5:20 am

    Product is fine, no issues. Only thing is i emailed a question and it took over a week to get back to me, was around new year to be fair

    Folliva Labs replied

    Sorry for the slow reply, that was the christmas week and we fell behind. Back to normal now, thanks for bearing with us.

  • B19 April 2026, 2:18 am

    scalp used to get flaky, way better now and the hair feels stronger

    Verified buyer

  • Vytautas Z.12 April 2026, 2:00 am

    asked a question by email, replied same day. good

    Folliva Labs replied

    Anytime, ask us whatever you need.

  • Anonymous12 April 2026, 12:40 am

    quick replies when i asked about the dose

    Verified buyer

  • Georgi Peeters9 April 2026, 12:37 am

    good

    Verified buyer

  • K.J.7 April 2026, 4:11 pm

    ordered late at night, shipped next morning

    Verified buyer

  • rasmus31 March 2026, 8:17 pm

    Received today, well packaged

    Verified buyer

  • georgi24 March 2026, 4:30 pm

    holding steady, no new bald patches which is a win at my age

    Verified buyer

  • Julius19 March 2026, 5:03 am

    slow going but the fall has definitely eased off

    Verified buyer

  • T.R.18 March 2026, 6:29 pm

    smooth order fast ship

    Verified buyer

  • Nils15 March 2026, 6:58 am

    arrived well packed, no issues

    Verified buyer

  • gubbe7 March 2026, 4:56 pm

    happy customer, quick turnaround

    Verified buyer

  • the_stig887 March 2026, 3:19 am

    Top, kam schnell an

  • Tomas Muller23 February 2026, 1:54 am

    early days, maybe 6 weeks, less falling out already though

  • Emre22 February 2026, 9:27 pm

    Thx for the quick shipping!!

  • Stefan8 February 2026, 4:55 pm

    6 months, thicker on top, no more seeing scalp under bright lights

    Verified buyer

  • Omar T.1 February 2026, 10:48 am

    Very friendly and quick, thanks!

  • Rasmus S.31 January 2026, 4:46 am

    Thanks! got here faster than i thought

    Verified buyer

  • P30 January 2026, 1:10 am

    Alles bestens, danke

    Verified buyer

  • Ivan R.21 January 2026, 10:35 pm

    definetly ordering again

    Verified buyer

  • H10 January 2026, 5:56 pm

    temples looked rough, now theres baby hairs filling them in. made up

    Verified buyer

  • Youssef Novak10 January 2026, 1:47 am

    no problems at all, recommend

  • S.B.9 January 2026, 8:05 pm

    reordered, same good service

    Folliva Labs replied

    Cheers for coming back.

  • kacper_p8 January 2026, 11:34 pm

    came in a plain box, perfect

    Verified buyer

  • hansi_13 December 2025, 8:36 pm

    Schnelle Lieferung, danke!

    Verified buyer

  • Marek30 November 2025, 10:12 am

    discreet package, appreciated

    Verified buyer

  • David Muller22 November 2025, 9:19 am

    finasteride wrecked my libido, this gave me zero sides. huge for me

    Verified buyer

  • Mateusz13 November 2025, 11:03 pm

    no fuss, on time

    Verified buyer

  • Oskar A.11 November 2025, 4:06 am

    only a couple weeks in so cant really say yet, no complaints though. will update

    Verified buyer

  • oskar31 October 2025, 9:01 am

    small hairs coming in at the temples, cant complain

    Verified buyer

  • Aleksander R.4 October 2025, 8:19 pm

    Received within the week, all good

    Verified buyer

  • Tobias26 September 2025, 12:03 pm

    keeps my hair as long as im consistent, skip a week and i can tell

    Verified buyer

  • lucas26 September 2025, 6:06 am

    Greitas pristatymas, ačiū

    Verified buyer

  • Z.J.16 September 2025, 1:46 pm

    bit of regrowth at the corners after 5 months, buzzing with that

  • jaybee15 September 2025, 7:20 am

    crown looks thicker in my photos, slow but its moving

    Verified buyer

  • Oskar13 September 2025, 1:02 pm

    danke, schnell geliefert

    Verified buyer

  • Sander13 September 2025, 1:16 am

    solid stuff, been the only thing to touch my crown

    Verified buyer

  • Tomas T.10 September 2025, 11:59 am

    9 months on it now, hairs better than its been in years. im 24, started losing it at 19

    Verified buyer

    Folliva Labs replied

    Class, really glad its working out for you. Cheers for the write up.

  • karim9 September 2025, 5:23 am

    cheap enough and it works, cant ask for more

    Verified buyer

  • Diego29 August 2025, 7:28 pm

    works if you actually use it every day, its not magic

  • Lars Novak26 August 2025, 1:34 pm

    got here in 4 days to lithuania

    Verified buyer

  • henrik16 August 2025, 8:28 am

    been on it half a year, take a pic every month, the difference month 1 to now is real

    Verified buyer

  • Z.B.13 August 2025, 6:07 pm

    good stuff quick delivery

    Verified buyer

  • Theo12 August 2025, 4:33 am

    3 months in and the hairloss has basically stopped. happy with that

    Verified buyer

  • david11 August 2025, 10:29 am

    first month i thought it was making it worse, turns out thats normal. month 4 now and its clearly better

    Verified buyer

  • Niklas M.30 July 2025, 2:05 pm

    Fast and discreet, thank you

  • lars29 July 2025, 6:07 am

    top service

    Verified buyer

  • two_stroke22 July 2025, 12:50 pm

    Perfect, thanks

    Verified buyer

  • Miguel H.13 July 2025, 11:04 pm

    not a miracle but my hair looks fuller than it did, ill take it

    Verified buyer

  • Omar J.6 July 2025, 7:31 pm

    bit slow to ship but no harm done

  • Niklas27 June 2025, 8:51 pm

    Prompt delivery no complaints

    Verified buyer

  • M27 June 2025, 3:14 pm

    got my package, thanks team

    Verified buyer

  • emre_3426 June 2025, 6:49 pm

    everything smooth, cheers

    Verified buyer

  • V19 June 2025, 12:16 pm

    hairline stopped moving back, thats honestly all i wanted

    Verified buyer

  • Edvinas D.2 June 2025, 12:12 pm

    arrived sealed with a date on it, good to see

    Verified buyer

  • Rasmus29 May 2025, 5:00 am

    third time buying here, always solid

    Verified buyer

  • Sami K.26 May 2025, 7:44 am

    good comms and fast dispatch

    Verified buyer

  • N.K.22 May 2025, 12:21 pm

    started this after two years of fin then minox. fin held my hair but messed with me too much so i stopped. minox was great for like 8 months then all the hair i saved started falling out at once, was grim. this was kind of a last try. first couple months nothing, then around month 3 the shed stopped and by month 6 there was actual regrowth on the crown. not 18 year old hair but way better. one less thing to stress about

    Verified buyer

    Folliva Labs replied

    Thanks for writing all that out, genuinely useful for people reading. Glad youre in a better spot with it.

  • Sami G.22 May 2025, 7:18 am

    used to weigh out my own powder and it was a nightmare, this is way easier and the same every time

    Verified buyer

  • z3ke20 May 2025, 4:34 am

    all good, sealed properly

    Verified buyer

  • Ruben J.28 April 2025, 11:35 am

    shipping quick, product as described

    Verified buyer

  • Mikkel Jansen27 April 2025, 5:29 am

    shed like crazy the first month and nearly stopped, glad i didnt, its calmed right down now

    Verified buyer

  • Mateusz N.13 April 2025, 3:52 pm

    honestly was skeptical, expected nothing, quietly surprised its working

    Verified buyer

  • Unknown12 April 2025, 3:00 am

    Livraison rapide, merci

    Verified buyer

  • Theo Kaiser9 April 2025, 2:38 am

    the itch went away first, then the shedding slowed down. good so far

  • Tijn M.29 March 2025, 6:35 am

    no more hair in the drain in the mornings, big difference for me

    Verified buyer

  • Mantas27 March 2025, 5:26 am

    ordered monday, here by thursday. nice

    Verified buyer

  • L22 March 2025, 3:45 pm

    Nice

    Verified buyer

  • D9 March 2025, 6:58 pm

    a bit greasy if you use too much, less is more. otherwise happy

    Verified buyer

  • M.W.26 February 2025, 7:09 am

    took me ages to find somewhere in the EU that ships RU without the customs nightmare, so glad i found these guys

    Verified buyer

  • Antoine J.15 February 2025, 3:51 pm

    Snelle levering, bedankt

    Verified buyer

  • nils_k14 February 2025, 7:01 pm

    cheers guys

    Verified buyer

  • Ruben Vos11 February 2025, 7:18 pm

    classic shed then regrowth, you just have to be patient with it

    Verified buyer

  • Antoine Vos8 February 2025, 5:40 pm

    my hairline was creeping back fast, its stopped now. thats enough for me

    Verified buyer

  • Bartek25 January 2025, 9:16 pm

    im 28, been thinning since 22, its finally slowed down after 4 months

    Verified buyer

  • Julius K.17 January 2025, 9:40 pm

    regrowth is patchy but its there, more than the pills ever did

    Verified buyer

  • Vytautas P.9 January 2025, 12:00 am

    Super quick, thanks alot

    Verified buyer

  • T.K.6 January 2025, 9:12 am

    fast shipping, thx

    Verified buyer

Write a review
YOUR RATING

Reviews are checked before they appear. We publish the honest ones. Good and bad.

HOW IT WORKS

What DHT does to a hair follicle.

Not stress. Not your shampoo. Not the water where you live. One hormone gives the same order to the follicle, cycle after cycle, and every time the hair comes back a little thinner. Here is the chain, and where this breaks it.
  1. 01

    DHT reaches the follicle

    Testosterone converts into DHT. In a susceptible scalp it binds androgen receptors inside the follicle. The receptor is the lock. DHT is the key.

  2. 02

    The follicle shrinks, cycle by cycle

    Every time that key turns, the growth phase gets shorter. Hair returns finer, shorter, weaker. That is miniaturisation, and it runs quietly for years before a mirror admits it.

  3. 03

    RU occupies the lock

    RU58841 is a nonsteroidal androgen receptor antagonist. It sits in the receptor so DHT cannot deliver its instruction — at the scalp, which is the only place the damage is happening.

  4. 04

    It is designed to work where you put it

    You apply it to skin. It is built to act locally rather than by lowering DHT across your whole body the way a daily pill does. That single difference is why most people arrive here from finasteride rather than instead of it.

Why waiting is the expensive part

A miniaturised follicle can still recover. A follicle that has finished the process cannot. Every cycle you wait, more of the first group quietly joins the second. That is not a sales tactic, it is arithmetic — and it is the only genuine reason to start sooner rather than later.

Why minoxidil on its own runs out of road

Minoxidil extends the growth phase. It does nothing whatsoever to the signal causing the loss. It is the accelerator, not the brake — you end up growing hair into a headwind, and the day you stop, the hair it borrowed goes back.

Diagram: DHT molecules docking into androgen receptors on a hair follicle, cross-section of scalp skin, labelled
WHERE IT STARTS

How hair loss starts.

Your body turns testosterone into a hormone called DHT. Inside every hair follicle there is a docking point for it — the keyhole in the picture.

When DHT locks into that docking point, the follicle is told to grow a thinner hair next time. That is the whole problem, and it happens under the skin. It is why shampoo, oils and a better diet do not reach it.

Your own body makes DHT — you cannot avoid producing it
The docking point is under the skin, inside the follicle
Diagram: four hair follicles over successive growth cycles showing progressive miniaturisation, labelled
WHAT HAPPENS NEXT

Hair does not fall out. It shrinks.

Each follicle in the picture is the same one, a growth cycle later. Every cycle the hair comes back thinner, shorter and lighter.

That is why you can lose a lot of hair before you ever see a bald spot — you simply have less of everything. A thinned follicle can still recover. One that has stopped completely cannot. That is the only honest reason not to leave it.

It runs for years before a mirror shows it
Thinned follicles can recover — finished ones cannot
Diagram: RU58841 occupying the androgen receptors on the follicle wall while DHT molecules cannot dock, labelled
WHAT RU DOES

You cannot stop your body making DHT. Where RU interrupts it

You cannot stop your body making DHT.

RU works the other way round — it sits in the docking point first, so DHT has nowhere to lock in.

The hormone still moves around your body exactly as before. It just cannot give the shrink order in that follicle. Worth being clear: it does not make hair grow. It removes the reason the hair was shrinking.

It blocks the docking point, not the hormone
It works in the skin you spray it on, once a day
Diagram comparing a topical spray acting in scalp tissue with an oral tablet carried through the bloodstream, labelled
SPRAY OR PILL

Why a spray and not a pill.

A pill has only one way to reach your scalp: lower DHT in your whole body. That is also where its side effects come from. These are the ones on finasteride's official label:

  • Reduced sex drive
  • Erection problems
  • Ejaculation problems
  • Breast tenderness and swelling
  • Low mood
  • In some men, symptoms that carry on after stopping

RU goes on your scalp and was built to work there.

Most people who write to us are coming off finasteride
THE ROUTINE

Sixty seconds, once a day.

Four steps, no device, nothing to rinse out.

  1. Start dry

    Back of a man's head with dry hair before applying the solution

    A clean, completely dry scalp. Water sitting on the skin dilutes the dose and carries it off.

  2. Apply

    Spraying the Folliva Labs solution onto a parted scalp

    Six to seven pumps is roughly 1 ml. Part the hair and put it on the skin, not the hair.

  3. Work it in

    Fingertips spreading the solution along a parted scalp

    Spread it across the thinning area with your fingertips. More is not better — the surplus buys irritation, not hair.

  4. Let it dry

    A parted scalp with the freshly applied solution still drying

    Give it a few minutes before a pillow or a hat. Wipe it off while it is still wet and it never gets into the skin at all.

Research compound. The batch documentation ships with your order.

Diagram: what happens inside a hair follicle month by month, from shedding through dormancy to a new growing shaft, labelled
THE FIRST SIX MONTHS

What happens while you see nothing.

Nothing shows in the mirror for a while, and that is normal. The follicle first has to finish shedding the hair it was holding, then rest, then start growing again.

Each of those steps takes weeks. That is why month two feels like failure, and why six months is the first fair moment to judge it.

Photograph the same spot, same light, on day one
Judge it at month six — photos, not memory
WHAT TO EXPECT

What to expect, month by month.

A follicle grows for years, rests, sheds and starts again — and the handovers are months apart, not days. That is the clock everything below runs on. Here is the honest sequence, including the month that makes most people give up three weeks before it would have started working.
  1. WEEKS 0–4

    Baseline — and possibly a shed

    Take your photographs on day one; you will not trust your memory later. Some people shed harder in the first weeks as follicles reset their cycle. It looks exactly like the product failing. It usually is not.

    A man photographing his own hairline in a bathroom mirror to record a baseline before starting
  2. MONTHS 1–2

    The shedding settles

    Loss slows before anything grows back. Nothing in the mirror rewards you yet. This is the stage most people never get past.

    A comb on a bathroom counter with a few loose hairs caught in it
  3. MONTHS 3–4

    First new growth

    Fine, pale hairs at the temples and hairline. Genuinely easy to miss without the baseline photo — which is the whole reason you took it.

    Macro of a hairline showing fine short pale hairs emerging alongside thicker pigmented hairs
  4. MONTH 6 AND BEYOND

    An honest verdict

    Six months is the earliest point a fair judgement is possible. Compare photographs, not memories. And be clear about what counts as a win: for a lot of people the result is that the recession stopped, not that it reversed.

    A man comparing two photographs of his hairline on his phone
THE OPTIONS

Everything you could take, side by side.

Mechanism, side effects, evidence and cost — including the columns that make us look worse.

Everything you could take, side by side.
FeatureRU-58841Topical antiandrogenOral finasterideSystemic DHT blockerMinoxidilTopical growth stimulantCB-03-01Clascoterone, topical antiandrogenPyrilutamideKX-826, topical antiandrogenKetoconazole shampooTopical antifungalGHK-CuCopper peptide, scalp supportNatural topicalsCaffeine, rosemary, saw palmettoDoing nothingBaseline
Mechanism
What it acts onThe androgen receptor5-alpha-reductase. Lowers DHTPotassium channels, blood flowThe androgen receptorThe androgen receptorFungus. Mildly, the receptorThe scalp skin itself. Not the hormoneSeveral weak effects. None well mapped
Where it actsScalpWhole bodyScalp. Some absorptionScalp. Broken down there by design, but measurable amounts still reach the bloodScalp, by designScalpScalpScalp
Side effects
No systemic or sexual side effectsPartlyDesigned to break down before it reaches the blood. No human data proves that it does.NoLower libido and erectile problems in a minority of men. Most recover after stopping. Some report that they did not. YesNot a hormonal drug. Rare heart-rate effects at high doses.PartlyBuilt to break down in the skin, but blood levels measured for their scalp solution are similar to the acne cream's, so a smaller treated area is not a safety argument. In the acne studies 3 of 42 had brief adrenal suppression that cleared after stopping.PartlyBuilt to act locally. In the trials, safety was no different from placebo. The data is still thin. YesTopical, barely absorbed YesA topical peptide. It does nothing to hormones, for better or worse. YesNothing here reaches your bloodstream in any amount that matters Yes
No scalp irritationPartlyThe alcohol carrier can dry or sting. That is the vehicle, not the compound. YesIt never touches your scalpNoItching and flaking are common. Mostly the propylene glycol.PartlyIn the hair trials local reactions matched the placebo liquid, but the placebo was the same carrier without the drug. The carrier is glycol-heavy and can dry the skin.PartlyUsually mild, but it does not suit everyonePartlyCan dry the scalp with regular use YesGenerally well tolerated on skin. Patch-test anyway. YesIn the rosemary trial, less itching than minoxidil. Yes
What it does
Blocks DHT YesAt the receptor. A non-steroidal molecule. YesLowers DHT at the sourceNoIt grows hair by a different route entirely YesAt the receptor. Same target, a steroidal molecule. YesAt the receptor. Same target, non-steroidal like RU-58841.PartlyA weak antiandrogen at bestNoNot an antiandrogen. It does nothing to DHT.PartlySaw palmetto is a weak 5-alpha-reductase inhibitorNo
An antiandrogen you apply, not swallow YesNoAn antiandrogen, but a tabletNoTopical, but not an antiandrogen Yes YesPartlyTopical, weakly antiandrogenicNoTopical, but not an antiandrogen at allPartlyTopical. Weakly, and only through saw palmetto.
Stimulates new growth on its ownNoIt takes the brake off. It adds nothing.NoSame idea: it removes suppression YesThis is the one thing it is forNoIt takes the brake off. It adds nothing of its own.NoSame route. It removes suppression.NoNoIt looks after the scalp. It does not push growth.PartlyA little, in small trials. Nothing like minoxidil.
Also works on the scalp itselfNoNoNoNoNo YesClears the flaking and inflammation. The only antifungal here. YesThis is the whole job of it: the condition of the skin your follicles grow fromPartlySome anti-inflammatory effect. It is not an antifungal.
Evidence and approval
An approved medicine for hair lossNoA research compound. No approved human use, anywhere. YesApproved, on prescription YesApproved for male-pattern hair lossNoThe same molecule has been an approved 1% acne cream in the US since 2020, but nothing containing it is approved for hair loss anywhere. Another company is expected to file in 2027.NoA research compound. No approved use, anywhere. The manufacturer is heading for a filing in China.PartlyApproved as an antifungal, not for hair lossNoA peptide sold in cosmetics. No medicine containing it is approved anywhere.NoCosmetics. Nobody has taken them through approval.
Human evidence behind itNoNo completed human trials. None. YesDecades of randomised trials, and the longest evidence base of anything on this table YesDecades of randomised trials YesTwo Phase 3 studies, 1,465 men, twelve months. Run by the company taking it through approval, on their formulation, not ours.PartlyPhase 3 trial data at 0.5% and 1.0%, which puts it ahead of most topicals. The results are the manufacturer's and are not yet published.PartlyA handful of small studiesPartlyReal human data, but in skin and wound healing. What exists for hair is thin.PartlyOne small trial matched rosemary oil to 2% minoxidil. Caffeine has a few. That is all of it.
Available without a prescription YesOnly because there is no approved use to prescribeNoPrescription only. A doctor has to agree. YesOver the counter YesNo approved hair-loss version to prescribe. The acne cream made from the same molecule is prescription only. YesSame reason again. There is no approved version to prescribe, anywhere.Partly1% over the counter. 2% is usually a prescription. YesNo approved medicine here to prescribe YesAny shop, any time
Living with it
If you stopLoss resumesLoss resumesShedding within weeksLoss resumesLoss resumesThe flaking comes backThe scalp goes back to how it wasBack to baseline
Daily effortOnce a dayOne tabletOnce or twice a dayTwice a dayOnce a dayTwo or three times a weekOnce a dayDaily, or every washNone
Cost per month, roughly€40–50€10–20€20–60€145 at 2.5%, €230 at 5%€60–90€5–10€90€10–25€0

A comparison of mechanisms, not medical advice. Minoxidil and finasteride are approved medicines with decades of randomised trials behind them, and finasteride has the longest evidence base of anything here. RU-58841, CB-03-01 and pyrilutamide are research compounds: none of them is an approved hair-loss medicine today. The Phase 3 figures quoted for clascoterone come from the formulation another company is taking through approval, not from ours, and no cortisol data from those hair trials has been published. The pyrilutamide trial results come from the manufacturer and are not yet published. GHK-Cu is a copper peptide included here as scalp support, not as a regrowth treatment. The natural column covers topical caffeine, rosemary oil and saw palmetto, where the human data is real but thin. Prices are rough monthly estimates and vary by dose, bottle size and brand, and each assumes the routine on that product's own page. Speak to a doctor before you start or stop anything.

FAQ

The questions people actually email us.

Is this the same thing as finasteride?

No. Finasteride is an approved oral medicine that lowers DHT throughout your body. This is a topical androgen receptor antagonist — it blocks the receptor at the scalp instead of lowering the hormone everywhere. Finasteride has decades of randomised trial data behind it and this does not, which is a genuine point in finasteride's favour and we are not going to hide it.

Why do people switch to it from finasteride?

Almost always because of how they felt on the pill. We are not going to make a safety claim we cannot support — there are no completed human trials here, so nobody can honestly tell you this is safer. What is true is that it is applied to the scalp rather than swallowed. Draw your own conclusion from that, and talk to a doctor if you are unsure.

How do I use it, and how much?

About 1 ml — six or seven pumps — on a dry scalp, once a day. Let it dry. That is the entire routine.

When would I see anything?

Less shedding somewhere in the first 4–8 weeks for most people, first new growth around month 3, and a fair verdict at month 6. If you judge it at week three you will judge it wrong.

My shedding got worse. Is it not working?

Early shedding is common as follicles reset their growth cycle, and it settles. It is also the single most common reason people bin a bottle that was about to start working. If it is still worsening at month three, write to us.

Are there side effects?

The honest answer is that nobody has run the trials that would tell you properly. Locally, scalp irritation and dryness are what people report most. Patch-test first, stop if you react, and do not use it if you are pregnant, breastfeeding or trying to conceive.

How do I know the bottle is genuine and fresh?

We blend it ourselves in the EU — not rebottled, not dropshipped, not sat in a warehouse. Lot number, blend date and expiry are on every bottle, and the independent assay for your lot is available on request. RU58841 degrades with time, so the age of the bottle in your hand is part of what you paid for.

Shipping, packaging and returns?

Ships from the EU, typically 3–5 days, in plain packaging with nothing on the outside indicating what is inside. Unopened bottles can be returned within 14 days.

What else the lab makes.

BLOCK Best Seller

RU58841 Topical Solution

4.9 (88)·5/8% · 30/50/100 ml

Occupies the androgen receptor so DHT cannot deliver its signal to the follicle.

This is the cause, not the symptom. On its own it will not push a dormant follicle back into growth.

From €39,99 View
ALTERNATE Sold out

Pyrilutamide 0.5% (KX-826)

4.6 (16)·0.5% w/v · 30 mL

A newer topical androgen-receptor antagonist. Different molecule, same target as RU-58841.

For people who do not tolerate RU. Run one blocker or the other, not both.

€90,00 Waitlist
ALTERNATE COMING SOON

CB-03-01 2.5/5% (Clascoterone)

2.5/5% · 50 ml

Blocks the androgen receptor at the follicle, then breaks down in the skin into an inactive form.

The only one here that finished phase 3. Clascoterone sold much cheaper elsewhere is usually weaker than the label says.

From €89,00 Waitlist
PUSH Sold out

Minoxidil 5%

4.6 (25)·5% · 60 mL

Extends the growth phase so follicles stay active longer. It does nothing to the hormone driving the loss.

Pairs with a blocker, never replaces one. Stop it and the growth it borrowed goes back.

€60,00 Waitlist
SUPPORT COMING SOON

Ketoconazole Shampoo

An antifungal wash that handles the flaking and irritation sitting underneath a lot of shedding.

Two or three washes a week, alongside a blocker. It is not a blocker itself.

€29,99 Waitlist
SUPPORT COMING SOON

GHK-CU Copper Peptide Spray

4.5 (13)·Copper peptide · 30 mL

A copper peptide that works on the condition of the scalp itself. Not an antiandrogen; it does nothing to DHT.

For scalp quality. On its own it will not hold a receding hairline.

€50,00 Waitlist
NATURAL COMING SOON

Natural Hair Regrowth Serum

4.6 (13)·Topical · 50 mL

Caffeine, rosemary and botanical oils. Scalp support, and the mildest thing in the range.

A leg of the routine, not the whole table. It does not block DHT.

€60,00 Waitlist